Browsing by Author "Verstraeten, Natalie"

A conserved GTPase induces membrane depolarization-triggered antibiotic tolerance

A historical perspective on bacterial persistence

A mutant isoform of ObgE causes cell death by irreversible arrest of the cell cycle at the onset of cell division

A mutant isoform of ObgE causes irreversible cell cycle arrest by blocking cell division

A single amino acid substitution in Obg activates a new programmed cell death pathway in Escherichia coli

A single amino acid substitution in Obg triggers programmed cell death in Escherichia coli

An integrated view of cell cycle control in Escherichia coli

Antibacterial activity of a new broad-spectrum antibiotic covalently bound to titanium surfaces

Biochemical determinants of ObgE-mediated persistence

Dynamics in evolvability and mortality drive evolution to high ethanol tolerance in Escherichia coli

Elucidation of the mode of action of a new antibacterial compound active against Staphylococcus aureus and Pseudomonas aeruginosa

Frequency of antibiotic application dictates rapid evolutionary adaptation of bacterial persistence

Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

GTP binding is necessary for the activation of a toxic mutant isoform of the essential GTPase ObgE

In vitro activity of the antiasthmatic drug zafirlukast against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans

In vitro emergence of high persistence upon periodic aminoglycoside challenge in the ESKAPE pathogens

ObgE* causes cell death by interfering with cell division

Rapid in vitro evolution of high antibiotic tolerance in the ESKAPE pathogens

Reactive oxygen species do not contribute to ObgE*-mediated programmed cell death

Repurposing AM404 for the treatment of oral infections by Porphyromonas gingivalis