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Whole Slide Imaging-Based Prediction of TP53 Mutations Identifies an Aggressive Disease Phenotype in Prostate Cancer

dc.contributor.authorPizurica, Marija
dc.contributor.authorLarmuseau, Maarten
dc.contributor.authorVan der Eecken, Kim
dc.contributor.authorDe Schaetzen van Brienen, Louise
dc.contributor.authorCarrillo-Perez, Francisco
dc.contributor.authorIsphording, Simon
dc.contributor.authorLumen, Nicolaas
dc.contributor.authorVan Dorpe, Jo
dc.contributor.authorOst, Piet
dc.contributor.authorVerbeke, Sofie
dc.contributor.authorGevaert, Olivier
dc.contributor.authorMarchal, Kathleen
dc.date.accessioned2023-11-17T08:13:24Z
dc.date.available2023-10-30T17:49:12Z
dc.date.available2023-11-17T08:13:24Z
dc.date.issued2023
dc.identifier.issn0008-5472
dc.identifier.otherWOS:001082528300005
dc.identifier.urihttps://imec-publications.be/handle/20.500.12860/43036.2
dc.sourceWOS
dc.titleWhole Slide Imaging-Based Prediction of TP53 Mutations Identifies an Aggressive Disease Phenotype in Prostate Cancer
dc.typeJournal article
dc.contributor.imecauthorPizurica, Marija
dc.contributor.imecauthorLarmuseau, Maarten
dc.contributor.imecauthorDe Schaetzen van Brienen, Louise
dc.contributor.imecauthorMarchal, Kathleen
dc.contributor.orcidimecPizurica, Marija::0000-0002-6653-4094
dc.contributor.orcidimecLarmuseau, Maarten::0000-0003-0466-099X
dc.contributor.orcidimecDe Schaetzen van Brienen, Louise::0000-0002-5882-9458
dc.contributor.orcidimecMarchal, Kathleen::0000-0002-2169-4588
dc.date.embargo2023-09-01
dc.identifier.doi10.1158/0008-5472.CAN-22-3113
dc.source.numberofpages15
dc.source.peerreviewyes
dc.source.beginpage2970
dc.source.endpage2984
dc.source.journalCANCER RESEARCH
dc.identifier.pmidMEDLINE:37352385
dc.source.issue17
dc.source.volume83
imec.availabilityPublished - open access
dc.description.wosFundingTextThe authors thank three anonymous reviewers for their useful remarks. The authors thank Cedric Vandemergel for scanning the histology slides of the UZ Ghent cohort and Pieter-Paul Strybol for technical support. The work was supported by grants of the Fonds Wetenschappelijk Onderzoek-Vlaanderen (FWO 3G045620), UGent BOF [BOF/IOP/2022/045 and 01J06219] and Flanders Innovation & Entrepreneurship (VLAIO, project "ATHENA," no. HBC.2019.2528). The research was further supported by the National Cancer Institute (NCI) under award: R01 CA260271. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. In addition, M. Pizurica was supported by a Fellowship of the Belgian American Educational Foundation and a grant from FWO 1161223N. M. Larmuseau was supported by a grant from FWO 3F013118. L. de Schaetzen van Brienen was supported by an FWO 3S037019. F. Carrillo-Perez was supported by the Spanish Ministry of Sciences, Innovation and Universities under Projects RTI-2018-101674-B-I00 and PID2021-128317OB-I00, the project from Junta de Andalucia P20-00163, and a predoctoral scholarship from the Fulbright Spanish Commission.


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