Publication:
Supramolecular Integration of 18-Crown-6 and an N-Capped Short Peptide Enables Multivalent Recognition and Modulation of Amyloid-β Proteotoxicity
| cris.virtual.department | #PLACEHOLDER_PARENT_METADATA_VALUE# | |
| cris.virtual.orcid | 0000-0002-2264-2536 | |
| cris.virtualsource.department | de48631c-19f8-4694-a94c-ceb8c31802d2 | |
| cris.virtualsource.orcid | de48631c-19f8-4694-a94c-ceb8c31802d2 | |
| dc.contributor.author | Chatterjee, Atin | |
| dc.contributor.author | Roy, Rajsekhar | |
| dc.contributor.author | Sarkar, Sandip | |
| dc.contributor.author | Sarkar, Soumyadeep | |
| dc.contributor.author | Chaini, Amlan | |
| dc.contributor.author | Roy, Arpan Narayan | |
| dc.contributor.author | Jana, Batakrishna | |
| dc.contributor.author | Ethirajan, Anitha | |
| dc.contributor.author | Pal, Uttam | |
| dc.contributor.author | Barman, Surajit | |
| dc.contributor.author | Ghosh, Surajit | |
| dc.contributor.author | Das, Amitava | |
| dc.date.accessioned | 2026-07-27T08:58:37Z | |
| dc.date.available | 2026-07-27T08:58:37Z | |
| dc.date.createdwos | 2026 | |
| dc.date.issued | 2026 | |
| dc.description.wosFundingText | AD acknowledges support from the ANRF J.C. Bose Fellowship (JBR/2023/000005) and MoE-STARS grant (2023-47). SG is supported by SERB/ANRF (CRG/2019/000670) and thanks Dr. Heera Ram (JNVU, Jodhpur) for assistance with animal studies. All animal experiments were approved by the Animal Ethics Committee, JNVU (UDZ/IAEC/2023/07). SG also thanks Central Research Facility (CRF) and IIT Jodhpur for infrastructural facilities. AC and RR thank CSIR-India and MHRD-India, respectively, for fellowships, and acknowledge IISER Kolkata for infrastructure, Bose Institute for access to the 700 MHz NMR facility. Additionally, we extend our gratitude to Mr. Tamal Ghosh, the other operators from the Department of Biological Sciences, and Mr. Soumya Sankha Biswas (NMR operator, Bose Institute) for their help with ITC , and HSQC experiments respectively. AC also thanks the BOF-BILA program (BOF21BL04) of Hasselt University. SS acknowledges UGC-India for fellowship support. A. Chaini and S. Sarkar thank CSIR-India and DST-Inspire, respectively. BJ acknowledges the SERB Ramanujan Fellowship (RJF/2022/000127). UP thanks Dr. N. C. Maiti for GPU computing access. SB acknowledges ICMR (45/35/2022-DDI/BMS) for a postdoctoral fellowship. It should be noted that portions of the schematic graphics and biological illustrations were created with BioRender.com under the publication license: SARKAR, S. (2026) https://BioRender.com/f92twys. | |
| dc.identifier.doi | 10.1021/jacs.6c03780 | |
| dc.identifier.eissn | 1520-5126 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.issn | 1520-5126 | |
| dc.identifier.pmid | MEDLINE:42339607 | |
| dc.identifier.uri | https://imec-publications.be/handle/20.500.12860/59982 | |
| dc.language.iso | eng | |
| dc.provenance.editstepuser | greet.vanhoof@imec.be | |
| dc.publisher | AMER CHEMICAL SOC | |
| dc.source.beginpage | 27260 | |
| dc.source.endpage | 27281 | |
| dc.source.issue | 26 | |
| dc.source.journal | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | |
| dc.source.numberofpages | 22 | |
| dc.source.volume | 148 | |
| dc.subject.keywords | MOLECULAR RECOGNITION | |
| dc.subject.keywords | AMINO-ACIDS | |
| dc.subject.keywords | AGGREGATION | |
| dc.subject.keywords | RESIDUES | |
| dc.subject.keywords | LYSINE | |
| dc.subject.keywords | COMPLEXATION | |
| dc.subject.keywords | CYTOTOXICITY | |
| dc.subject.keywords | OLIGOMER | |
| dc.subject.keywords | FIBRILS | |
| dc.title | Supramolecular Integration of 18-Crown-6 and an N-Capped Short Peptide Enables Multivalent Recognition and Modulation of Amyloid-β Proteotoxicity | |
| dc.type | Journal article | |
| dspace.entity.type | Publication | |
| imec.internal.crawledAt | 2026-06-25 | |
| imec.internal.source | crawler | |
| imec.internal.wosCreatedAt | 2026-07-14 | |
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