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Adoption of microfluidic MEA technology for electrophysiology of 3D neuronal networks exposed to suborbital conditions

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dc.contributor.authorPadilla, Andie E.
dc.contributor.authorGobinath, G.
dc.contributor.authorHovell, Candice
dc.contributor.authorMares, Jeremy
dc.contributor.authorReumers, Veerle
dc.contributor.authorClements, Twyman
dc.contributor.authorRextroat, Jason
dc.contributor.authorGamble, Paul
dc.contributor.authorLumpp, Ben
dc.contributor.authorJoddar, Binata
dc.date.accessioned2025-06-01T05:32:44Z
dc.date.available2025-06-01T05:32:44Z
dc.date.issued2025-MAY 27
dc.description.wosFundingTextThe authors gratefully acknowledge the support provided by the NIH-NIMHD-RCMI Grant No. 5G12MD007592, which facilitated the utilization of the confocal microscopy facility in the BBRC at UTEP. This study was funded via a NASA REDDI grant (#80NSSC21K0336) to BJ via IMEC, USA. The authors would also like to thank the 3DMPSL, headed by Dr. Natividad Diaz, for access to the FormLabs 3B SLA printer. We thank research technician Ms. Carla D. Loyola in IMSTEL for her help with qPCR and analysis. We also gratefully acknowledge help from Ms. Ivana Hernandez for the normalization processing of fluorescent images for Fig. 5 using ImageJ. Jason Rextroat, Twyman Clements, Paul Gamble, and Ben Lumpp are included as co-authors for the development of the CubeLab system, which maintained our samples during the suborbital flight. Without the CubeLab, the study would not have been feasible.
dc.identifier.doi10.1038/s41526-025-00476-x
dc.identifier.pmidMEDLINE:40425594
dc.identifier.urihttps://imec-publications.be/handle/20.500.12860/45743
dc.publisherNATURE PORTFOLIO
dc.source.issue1
dc.source.journalNPJ MICROGRAVITY
dc.source.numberofpages12
dc.source.volume11
dc.title

Adoption of microfluidic MEA technology for electrophysiology of 3D neuronal networks exposed to suborbital conditions

dc.typeJournal article
dspace.entity.typePublication
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